NeuroscienceACS Chemical NeurosciencePeer-reviewed
Mechanisms of Alpha-Synuclein Seeded Aggregation in Neurons Revealed by Fluorescence Lifetime Imaging
Paula-Marie E. Ivey, Magaly Guzman Sosa, Abdelrahman M. Salem…·Kevin John Webb
This study uses fluorescence lifetime imaging to track alpha-synuclein aggregation in neurons, revealing that seeds disassemble before escaping endolysosomes and triggering cytosolic aggregation.
5 citations