Author

Wiebke Obermann

Philipps University of Marburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Arnold GrünwelleriD· 3 shared F. MagariiD· 2 shared Gaspar Taroncher‐OldenburgiD· 2 shared Leonie Konopka· 2 shared Marc F. ScheteligiD· 2 shared A. HeineiD· 1 shared Ana Rodrı́gueziD· 1 shared Andreas H. Ludewig· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Arnold GrünwellerORCID

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3 papers

Recent·Most cited

The RNA helicase eIF4A as a novel target in insect cells to combat arboviral infections

Tanja Rehling, Kim Mentchen, Leonie Konopka, Wiebke Obermann, Friedemann Weber, Patrick Schmerer, Marc F. Schetelig, Arnold Grünweller, Irina Häecker, F. Magari

This paper identifies eIF4A as a druggable host factor in insect vectors that can be targeted by rocaglates and pateamines to suppress arboviral replication.

PLoS ONE · Apr 6, 2026Peer-reviewedMolecular Biology

In silico, biochemical, and in vitro analysis of silvestrol binding to the DEAD box RNA helicase eIF4A reveals broad anti-pathogen potential of rocaglates across the eukaryotic tree of life

Wiebke Obermann, Mohammad Farhan Darin Azri, Leonie Konopka, Nina Schmidt, F. Magari, Julian Sherman, Liliana M. R. Silva, Carlos Rodrigo Hermosilla, Andreas H. Ludewig, Hicham Houhou, Simone Haeberlein, Mona Yiting Luo, Irina Häcker, Marc F. Schetelig, Christoph Gero Grevelding, , Gaspar Taroncher‐Oldenburg

The paper analyzes eIF4A sequence variants across eukaryotes to assess rocaglate sensitivity, revealing broad anti-pathogen potential and resistance patterns.

bioRxiv · Sep 9, 2022 · PreprintMolecular Biology

The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo

Christin Müller, Wiebke Obermann, Nadja Karl, Hans‐Guido Wendel, Gaspar Taroncher‐Oldenburg, Stephan Pleschka, Roland Karl Hartmann, Arnold Grünweller, John Ziebuhr

Antiviral Research · Jan 8, 2021Peer-reviewedMolecular Biology