Cycling Molecular Assemblies for Selective Cancer Cell Golgi Disruption
Weiyi Tan, Qiuxin Zhang, Zhiyu Liu, Kangqiang Qiu, Divyanshu Mahajan, Thomas J. Gerton, Noah Copperman, Erica C. Dresselhaus, Chaoshuang Xia, Cheng Lin, William Lau, Mikki Lee, Isabela Ashton-Rickardt, Pengyu Hong, Daniela M. Dinulescu, , Bing Xu
This paper develops CyMA, small peptides that disrupt cancer cell Golgi function by exploiting enzymatic cycles, showing selectivity over hepatocytes and immune cells.
Nature Communications · Jan 28, 2026Peer-reviewedBiochemistry