CRISPR editing of candidate host factors that impact influenza A virus infection
Pyae Phyo Kyawe, Ping Liu, Zhaozhao Jiang, Evan Stuart Bradley, Thomas Cicuto, Melanie I. Trombly, Neal S. Silverman, Katherine A. Fitzgerald, William M. McDougall, Jennifer P Wang
This paper uses CRISPR to test host factors affecting influenza A virus infection, finding that CMAS knockout and B4GALNT2 overexpression restrict IAV, while ADAR1 overexpression has a pro-viral effect on CVB.
Microbiology Spectrum · Jan 31, 2025Peer-reviewedImmunology