Zhaozhao Jiang

Alternative cGAS signaling promotes Herpes simplex encephalitis

This study identifies an alternative cGAS signaling pathway independent of cGAMP that promotes neutrophil recruitment and viral dissemination in herpes simplex encephalitis.

CRISPR editing of candidate host factors that impact influenza A virus infection

This paper uses CRISPR to test host factors affecting influenza A virus infection, finding that CMAS knockout and B4GALNT2 overexpression restrict IAV, while ADAR1 overexpression has a pro-viral effect on CVB.

CNBP controls c-Rel dependent IL-12 β gene transcription and Th1 immunity

This study identifies CNBP as a regulator of c-Rel dependent IL-12β gene transcription and Th1 immunity, showing its role in macrophage function and resistance to toxoplasmosis.