Author

Wolfgang Maier

University of Bonn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genetics· 4 Genetic & Genomic Medicine· 1 Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Assay:GWAS summary statistics· 5 Approach:statistical model· 5 Research Focus:GWAS / association mapping· 3 Research Focus:polygenic risk· 3 Assay:bulk RNA-seq· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Daniel SoueryiD· 4 shared Joanna HauseriD· 4 shared Marcella RietscheliD· 4 shared Neven HenigsbergiD· 4 shared Peter McGuffiniD· 4 shared Rudolf UheriD· 4 shared Cathryn M. LewisiD· 3 shared Chiara FabbriiD· 3 shared

Activity by Year

2017-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetics

Daniel SoueryORCID

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Author profile →

7 papers

Recent·Most cited

The neuropeptide neuromedin U receptor nmur-1 buffers insulin receptor signaling in bacteria-dependent C. elegans survival

Deniz Sifoglu, Bianca Pereira, Christina DeGregory, Rahi Shah, Wolfgang Maier, Joanne Guan, Ian Clark, Dhaval S Patel, Quee-Lim Ch'ng, Joy Alcedo

This study shows that the neuropeptide receptor NMUR-1 modulates insulin receptor signaling in C. elegans to buffer survival differences caused by bacterial strains.

PLoS Genetics · Jun 11, 2026Peer-reviewedPhysiology

Meta-analysis of CYP2C19 and CYP2D6 metabolic activity on antidepressant response from 13 clinical studies using genotype imputation

Danyang Li, Oliver Pain, Chiara Fabbri, Win Lee Edwin Wong, Chris Wai Hang Lo, Stephan Ripke, Annamaria Cattaneo, Daniel Souery, Mojca Zvezdana Dernovšek, Neven Henigsberg, Joanna Hauser, Glyn Lewis, Ole Mors, Nader Perroud, Marcella Rietschel, , Cathryn M. Lewis

This study examines the association between CYP2C19 and CYP2D6 metabolic phenotypes and antidepressant response using genotype imputation across 13 studies, finding no significant associations after correction for multiple testing.

Translational Psychiatry · Jul 18, 2024Peer-reviewedGenetic & Genomic Medicine

Applying polygenic risk scoring for psychiatric disorders to a large family with Bipolar Disorder and Major Depressive Disorder

Simone de Jong, Mateus Jose Abdalla Diniz, Andiara Saloma, Ary Gadelha, Marcos Leite Santoro, Vanessa Ota, Cristiano de Souza Noto, Naomi R. Wray, Stephan Ripke, Manuel Mattheisen, Maciej Trzaskowski, Enda M. Byrne, Abdel Abdellaoui, Mark J. Adams, Esben Agerbo, , Jodie N. Painter

The paper applies polygenic risk scoring to a large family with bipolar and depressive disorders to study genetic risk patterns and anticipation.

Communications Biology · Oct 2, 2018Peer-reviewedGenetics

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: meta-analysis of data from genome-wide association studies

Chiara Fabbri, Katherine E. Tansey, Roy H. Perlis, Joanna Hauser, Neven Henigsberg, Wolfgang Maier, Ole N Mors, Anna Placentino, Marcella Rietschel, Daniel Souery, Gerome D. Breen, Charles J. C. Curtis, Sang‐Hyuk Lee, Stephen Newhouse, Hamel Patel, , Cathryn M. Lewis

This paper conducts a meta-analysis showing that CYP2C19 poor metabolizers have better antidepressant efficacy but similar side effects compared to extensive metabolizers.

European Neuropsychopharmacology · Jun 28, 2018Peer-reviewedGenetics

Assessing 42 inflammatory markers in 321 control subjects and 887 major depressive disorder cases: BMI and other confounders and overall predictive ability for current depression

Timothy R. Powell, Helena Gaspar, Raymond Chung, Aoife Keohane, Cerisse Gunasinghe, Rudolf Uher, Katherine Jean Aitchison, Daniel Souery, Ole N Mors, Wolfgang Maier, Astrid W. Zobel, Marcella Rietschel, Neven Henigsberg, Mojca Zvezdana Dernovšek, Joanna Hauser, , Hong Wang

The paper evaluates 42 inflammatory markers in MDD cases and controls, finding strong confounding effects and limited predictive power of individual markers for MDD diagnosis.

bioRxiv · May 21, 2018 · PreprintNeuroscience

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

eQTLGen, Naomi R. Wray, 23andMe, Stephan Ripke, Manuel Mattheisen, Maciej Trzaskowski, Enda M. Byrne, Abdel Abdellaoui, Mark J. Adams, Esben Agerbo, Tracy Air, Till F. M. Andlauer, Silviu‐Alin Bacanu, Marie Bækvad‐Hansen, Aartjan T.F. Beekman, , Niamh Mullins

Genome-wide association meta-analysis of 130,664 major depression cases and 330,470 controls identifies 44 independent risk loci enriched in cortical neurons, conserved mammalian regions, splicing networks, and antidepressant targets.

Nature Genetics · Apr 26, 2018Peer-reviewedGenetics✦ In-depth digest

Pharmacogenetics of antidepressant response: a polygenic approach

Judit García‐González, Katherine E. Tansey, Joanna Hauser, Neven Henigsberg, Wolfgang Maier, Ole N Mors, Anna Placentino, Marcella Rietschel, Daniel Souery, Tina Žagar, Piotr M. Czerski, Borut Jerman, Henriette N. Buttenschøn, Thomas G. Schulze, Astrid W. Zobel, , Chiara Fabbri

This study investigates whether polygenic risk scores (PRS) can predict antidepressant response in MDD, finding no significant predictive effect.

Progress in Neuro-Psychopharmacology and Biological Psychiatry · Jan 31, 2017Peer-reviewedGenetics