Author

Woonghee Kim

Science for Life Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Systems Biology· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:rat· 2 Approach:experimental assay· 1 Assay:metabolomics· 1

Frequent Co-Authors

Adil MardinoğluiD· 4 shared Cheng ZhangiD· 4 shared Hasan TürkeziD· 4 shared Jan BoréniD· 4 shared Mathias UhléniD· 4 shared Jens NielseniD· 3 shared Muhammad ArifiD· 3 shared Xiangyü LiiD· 3 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersSystems Biology

Adil MardinoğluORCID

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4 papers

Recent·Most cited

Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats

Hong Yang, Cheng Zhang, Woonghee Kim, Mengnan Shi, Metin Kılıçlıoğlu, Cemil Bayram, İsmail Bolat, Özlem Özdemir Tozlu, Cem Baba, Nursena Yuksel, Serkan Yıldırım, Shazia Iqbal, Jihad Sebhaoui, Ahmet Hacımüftüoğlu, Mathias Uhlén, , Adil Mardinoğlu

This study investigates the effects of JNK inhibition on metabolic dysfunction caused by sucrose overconsumption in rats using multi-tissue network analysis.

eLife · Feb 11, 2025Peer-reviewedBioinformatics

Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning

Cheng Zhang, Mengnan Shi, Woonghee Kim, Muhammad Arif, Martina Klevstig, Xiangyü Li, Hong Yang, Cemil Bayram, İsmail Bolat, Özlem Özdemir Tozlu, Ahmet Hacımüftüoğlu, Serkan Yıldırım, Jihad Sebhaoui, Shazia Iqbal, Yongjun Wei, , Adil Mardinoğlu

This study identifies PKLR as a therapeutic target for NAFLD and validates two drug candidates through in vitro and in vivo experiments.

EBioMedicine · Aug 18, 2022Peer-reviewedSystems Biology

Discovery of functional alternatively spliced PKM transcripts in human cancers

Xiangyü Li, Cheng Zhang, Woonghee Kim, Muhammad Arif, Chunxia Gao, Andreas Hober, David Kotol, Linnéa Strandberg, Björn Forsström, Åsa Sivertsson, Per Oksvold, Hasan Türkez, Morten Grøtli, Yusuke Sato, Haruki Kume, , Adil Mardinoğlu

The paper investigates the prognostic significance of PKM transcripts in 25 cancers and identifies a prognostic signature in KIRC, revealing functional roles of alternatively spliced PKM transcripts.

Cancers · Jan 19, 2021Peer-reviewedSystems Biology

Classification of clear cell renal cell carcinoma based on PKM alternative splicing

Xiangyü Li, Beste Turanlı, Kajetan Juszczak, Woonghee Kim, Muhammad Arif, Yusuke Sato, Seishi Ogawa, Hasan Türkez, Jens Nielsen, Jan Borén, Mathias Uhlén, Cheng Zhang, Adil Mardinoğlu

The paper identifies two ccRCC subtypes based on PKM alternative splicing and proposes drug repurposing for each subtype.

Heliyon · Feb 1, 2020Peer-reviewedSystems Biology