A Mycobacterium tuberculosis effector protein attacks host innate immunity by acting as an unusual ubiquitinating enzyme
J. Wang, P. Ge, Z. Lei, L. Qiang, Q. Chai, Y. Zhang, Z. Lu, D. Zhao, B. Li, J. Su, R. Peng, Y. Pang, Y. Shi, G. F. Gao, X.-B. Qiu, C. H. Liu
This paper shows that Mtb PknG acts as an unusual ubiquitinating enzyme by promoting ubiquitination of TRAF2 and TAK1 to suppress host innate immunity.
bioRxiv · Nov 5, 2020 · PreprintMicrobiology