Author

Q. Chai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Li· 1 shared B. M. Peterlin· 1 shared C. H. Liu· 1 shared D. A. Frabutt· 1 shared D. Zhao· 1 shared G. F. Gao· 1 shared I. Ahmad· 1 shared J. F. Hultquist· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

B. Li

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2 papers

Recent·Most cited

HIV-1 Nef and CycK:CDK13 antagonize SERINC5 for optimal viral infectivity

Q. Chai, S. Li, M. K. Collins, R. Li, I. Ahmad, S. F. Johnson, D. A. Frabutt, Z. Yang, X. Shen, L. Sun, J. Hu, J. F. Hultquist, B. M. Peterlin, Y.-H. Zheng

This study identifies CycK:CDK13 as a kinase complex that phosphorylates SERINC5 at S360, enhancing Nef-mediated downregulation and counteracting its antiviral activity.

bioRxiv · May 24, 2021Microbiology

A Mycobacterium tuberculosis effector protein attacks host innate immunity by acting as an unusual ubiquitinating enzyme

J. Wang, P. Ge, Z. Lei, L. Qiang, Q. Chai, Y. Zhang, Z. Lu, D. Zhao, B. Li, J. Su, R. Peng, Y. Pang, Y. Shi, G. F. Gao, X.-B. Qiu, C. H. Liu

This paper shows that Mtb PknG acts as an unusual ubiquitinating enzyme by promoting ubiquitination of TRAF2 and TAK1 to suppress host innate immunity.

bioRxiv · Nov 5, 2020 · PreprintMicrobiology