Author

X.-M. Yin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Khambu· 3 shared G. Liu· 2 shared X. Chen· 2 shared Z. Dong· 2 shared A. K. Bryan· 1 shared A. Mercer· 1 shared C. K. Harvest· 1 shared E. A. Miao· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersPharmacology & Toxicology

B. Khambu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Apoptotic signaling clears engineered Salmonella in an organ-specific manner

T. J. Abele, Z. P. Billman, L. Li, C. K. Harvest, A. K. Bryan, G. R. Magalski, J. P. Lopez, H. N. Larson, X.-M. Yin, E. A. Miao

This study shows that apoptosis and pyroptosis clear engineered Salmonella from different organs in mice, with pyroptosis being more effective in myeloid niches and apoptosis in the intestinal niche.

bioRxiv · May 6, 2023 · PreprintImmunology

Impaired hepatic autophagy exacerbates xenobiotics induced liver injury

K. Byrnes, N. T. Bailey, A. Mercer, S. Joshi, G. Liu, X.-M. Yin, B. Khambu

This study shows that impaired hepatic autophagy worsens xenobiotic-induced cholestatic liver injury by promoting p62-Ub-IHB accumulation and suppressing FXR.

bioRxiv · May 27, 2022 · PreprintPharmacology & Toxicology

Gut dysbiosis protects against liver injury in autophagy deficient mice by FXR-FGF15 feedback signaling

S. Yan, B. Khambu, X. Chen, Z. Dong, G. Guo, X.-M. Yin

This study shows that gut dysbiosis reduces liver injury in autophagy-deficient mice through FXR-FGF15 signaling, suggesting caution in antibiotic use during liver disease.

bioRxiv · May 12, 2020Pathology

The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors

B. Khambu, H. Hong, S. Liu, G. Liu, X. Chen, Z. Dong, J. Wan, X.-M. Yin

This study investigates how HMGB1 and RAGE promote tumor growth in autophagy-deficient livers by altering the tumor microenvironment and mitochondrial function.

bioRxiv · Nov 25, 2019Cancer Biology