X.-Y. Zhou

Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response

This study shows that fish CDK2 recruits Dtx4 to ubiquitinate and degrade TBK1, reducing IFN expression and enhancing antiviral resistance.

Microbiome Analysis of the Eastern Oyster As a Function of Ploidy and Seasons

The paper analyzes the microbiome of eastern oysters (Crassostrea virginica) across ploidy and seasons, finding Psychrobacter as a dominant genus with functional roles in nitrogen cycling.

Autophagy-associated Production of Antimicrobial Peptides hBD1 and LL37 Exhibits Anti-Bacillus Calmette-Guerin Effects in Lung Epithelial Cells.

The paper shows that autophagy in lung epithelial cells enhances the production of antimicrobial peptides hBD1 and LL37, which kill intracellular Mycobacterium tuberculosis.

Grass Carp Reovirus (GCRV) Giving Its All to Suppress IFN Production by Countering MAVS-TBK1 Activation .

This paper identifies how GCRV proteins interact with fish RLR factors to suppress MAVS-TBK1 signaling and reduce IFN expression, revealing a unique fish virus evasion mechanism.

Desiccation Does Not Drastically Increase the Accessibility of Foreign DNA to the Nuclear Genomes: Evidence from the Frequency of Endosymbiotic DNA Transfer

The paper investigates whether desiccation increases foreign DNA integration into nuclear genomes by analyzing NUMT and NUPT abundance in desiccation-tolerant and sensitive organisms, finding no significant increase.