Author

H.-l. Liu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

B. Zheng· 1 shared C. Yan· 1 shared C.-Y. Fan· 1 shared D. Ma· 1 shared F. Fang· 1 shared J. Wu· 1 shared J.-h. Yang· 1 shared J.-k. Wen· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

B. Zheng

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multiscale mechanical models of DNA nanotubes: A theoretical basis for the design and tuning of DNA nanocarriers

H.-L. Liu, N.-H. Zhang, W. Lu

This paper develops a multiscale model to predict and control mechanical properties of DNA nanotubes for improved drug carrier design.

bioRxiv · Dec 12, 2021 · PreprintBiophysics

Autophagy-associated Production of Antimicrobial Peptides hBD1 and LL37 Exhibits Anti-Bacillus Calmette-Guerin Effects in Lung Epithelial Cells.

R.-n. Wang, H.-l. Liu, Y.-x. Chen, Q. Wen, X.-y. Zhou, J.-l. Wang, J.-h. Yang, Y.-f. Li, Z.-y. Han, L. Ma

The paper shows that autophagy in lung epithelial cells enhances the production of antimicrobial peptides hBD1 and LL37, which kill intracellular Mycobacterium tuberculosis.

bioRxiv · Feb 21, 2020 · PreprintImmunology

CsHscB as a novel TLR2 agonist from carcinogenic liver fluke Clonorchis sinensis modulates host immune response

C. Yan, F. Fang, Y.-Z. Zhang, J. Wu, X. Dong, H.-L. Liu, C.-Y. Fan, Q. Yu, L. Wang, X.-Y. Li, Y. Wang, J.-X. Chen, R.-X. Tang, K.-Y. Zheng

The paper identifies CsHscB from Clonorchis sinensis as a TLR2 agonist that modulates macrophage activation and IL-10 production through TLR2-dependent mechanisms.

bioRxiv · Nov 29, 2019 · PreprintImmunology

eIF5a reduction via decreased Klf5 leads to cell senescence by mitochondrial fission in VSMCs

D. Ma, B. Zheng, H.-l. Liu, Y.-b. Zhao, X. Liu, X. Zhang, Q. Li, W.-b. Shi, T. Suzuki, J.-k. Wen

This study shows that Klf5 downregulation in VSMCs leads to mitochondrial fission and senescence by reducing eIF5a, which preserves mitochondrial integrity.

bioRxiv · Sep 30, 2019 · PreprintBiochemistry