Author

Xian C Jiang

SUNY Downstate Health Sciences University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Céline Cruciani‐GuglielmacciiD· 1 shared Chloé AmouyaliD· 1 shared Chr̀istophe MagnaniD· 1 shared Eleni GeorgiadouiD· 1 shared F. MifsudiD· 1 shared Guy A. RutteriD· 1 shared Hervé Le StunffiD· 1 shared Ilyès RahoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Céline Cruciani‐GuglielmacciORCID

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1 paper

Recent·Most cited

Serine palmitoyltransferase-mediated de novo sphingolipid biosynthesis is required for normal insulin production and glucose tolerance

Chloé Amouyal, Shiou Ping Chen, Jessica Denom, Ilyès Raho, Nadim Kassis, Marc Diedisheim, F. Mifsud, Justine Lallement, Eleni Georgiadou, Mark R. Ibberson, Mikaël Croyal, Xian C Jiang, Céline Cruciani‐Guglielmacci, Hervé Le Stunff, Guy A. Rutter, Chr̀istophe Magnan

This study shows that de novo ceramide synthesis in beta-cells is essential for normal insulin production and glucose tolerance, as its inhibition leads to reduced beta-cell mass and impaired glucose regulation.

bioRxiv · May 14, 2025 · PreprintPhysiology