Author

Nadim Kassis

Centre National de la Recherche ScientifiqueORCID 0000-0002-5013-0132Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Céline Cruciani‐GuglielmacciiD· 2 shared Chr̀istophe MagnaniD· 2 shared Mikaël CroyaliD· 2 shared Chloé AmouyaliD· 1 shared David RibetiD· 1 shared Eleni GeorgiadouiD· 1 shared F. MifsudiD· 1 shared Gilles MithieuxiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersPhysiology

Céline Cruciani‐GuglielmacciORCID

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2 papers

Recent·Most cited

Contributions of the gut microbiota and intestinal gluconeogenesis to metabolic adaptations in a mouse model of anorexia nervosa.

Shiou-Ping Chen, Zahra Boudra, Nadim Kassis, Soham Saha, Stéphanie Billon‐Crossouard, Justine Vily‐Petit, David Ribet, Pierre-Yves Barelle, Mikaël Croyal, Nicolás Ramoz, Virginie Tolle, Moı̈se Coëffier, Odile Viltart, Gilles Mithieux, Chr̀istophe Magnan, Céline Cruciani‐Guglielmacci

This study investigates how food restriction in a mouse model of anorexia nervosa affects gut microbiota and intestinal gluconeogenesis, revealing their roles in maintaining glucose homeostasis.

bioRxiv · Sep 21, 2026 · PreprintPhysiology

Serine palmitoyltransferase-mediated de novo sphingolipid biosynthesis is required for normal insulin production and glucose tolerance

Chloé Amouyal, Shiou Ping Chen, Jessica Denom, Ilyès Raho, Nadim Kassis, Marc Diedisheim, F. Mifsud, Justine Lallement, Eleni Georgiadou, Mark R. Ibberson, Mikaël Croyal, Xian C Jiang, Céline Cruciani‐Guglielmacci, Hervé Le Stunff, Guy A. Rutter, Chr̀istophe Magnan

This study shows that de novo ceramide synthesis in beta-cells is essential for normal insulin production and glucose tolerance, as its inhibition leads to reduced beta-cell mass and impaired glucose regulation.

bioRxiv · May 14, 2025 · PreprintPhysiology