Author

Jessica Denom

Centre National de la Recherche ScientifiqueORCID 0000-0002-8507-058XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Céline Cruciani‐GuglielmacciiD· 2 shared Chr̀istophe MagnaniD· 2 shared Aleksandra MieczkowskaiD· 1 shared Chloé AmouyaliD· 1 shared Eleni GeorgiadouiD· 1 shared Emma K. Biggs· 1 shared F. MifsudiD· 1 shared Fiona Mary GribbleiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPhysiology

Céline Cruciani‐GuglielmacciORCID

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2 papers

Recent·Most cited

PhysiologyAmerican Journal of Physiology-Endocrinology and MetabolismPeer-reviewedAug 12, 2025

The GLP-1 analogue, exendin-4, improves bone material properties and strength through a central relay in ovariectomized mice

Morgane Mermet, Jessica Denom, Aleksandra Mieczkowska…·Guillaume Mabilleau

This study shows that exendin-4 improves bone strength in ovariectomized mice through a central mechanism, not directly on bone cells.

3 citations

mouseexperimental assay

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PhysiologybioRxivPreprintMay 14, 2025

Serine palmitoyltransferase-mediated de novo sphingolipid biosynthesis is required for normal insulin production and glucose tolerance

Chloé Amouyal, Shiou Ping Chen, Jessica Denom…·Chr̀istophe Magnan

This study shows that de novo ceramide synthesis in beta-cells is essential for normal insulin production and glucose tolerance, as its inhibition leads to reduced beta-cell mass and impaired glucose regulation.

DOI 10.1101/2025.05.14.653935

mousebulk RNA-seq

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