Author

Xiaohua Wu

Broad Institute

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Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:plant (other)· 1 Assay:proteomics· 1

Frequent Co-Authors

Alice H. BergeriD· 1 shared Alykhan F. Shamji· 1 shared Andrew A. TubelliiD· 1 shared Angela Norie BrooksiD· 1 shared Anita VrciciD· 1 shared Aravind SubramanianiD· 1 shared Arthur Liberzon· 1 shared Bang Wong· 1 shared

Activity by Year

2017-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Alice H. BergerORCID

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2 papers

Recent·Most cited

Environmental polysulfides promote protein disulfide bond formation of microorganisms growing under anaerobic condition

Yuping Xin, Qingda Wang, Jianming Yang, Xiaohua Wu, Yongzhen Xia, Luying Xun, Huaiwei Liu

The paper shows environmental polysulfides promote protein disulfide bond formation in anaerobic microorganisms, aiding their survival.

Applied and Environmental Microbiology · Feb 7, 2025Peer-reviewedMolecular Biology

A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles

Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, David D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie K. Donahue, Bina Julian, , Todd R. Golub

The paper introduces the L1000 platform, a high-throughput gene expression profiling method, and reports 1.3 million perturbational profiles expanding the Connectivity Map for drug mechanism discovery and functional annotation.

Cell · Nov 1, 2017Peer-reviewedGenomics