Author

Xiaoyu Hong

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:imaging· 1 Organism:virus· 1

Frequent Co-Authors

Qiaoyu ZhaoiD· 2 shared Yanxing WangiD· 2 shared Caixuan LiuiD· 1 shared Chao ZhangiD· 1 shared Cong XuiD· 1 shared Cong Yao· 1 shared Fangfang WangiD· 1 shared Hong QiniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

Qiaoyu ZhaoORCID

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2 papers

Recent·Most cited

Development of immobilized antibody-based affinity grid strategy and application in on-grid purification of target proteins for high-resolution cryo-EM

Qiaoyu Zhao, Xiaoyu Hong, Yanxing Wang, Shaoning Zhang, Zhanyu Ding, Xueming Meng, Qianqian Song, Qin Hong, Wanying Jiang, Xiangyi Shi, Tianxun Cai, Cong Yao

The paper develops an immobilized antibody-based affinity grid strategy to improve cryo-EM sample preparation by enabling on-grid purification of target proteins and overcoming orientation issues.

bioRxiv · Jan 17, 2024 · PreprintMolecular Biology

Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM

Cong Xu, Yanxing Wang, Caixuan Liu, Chao Zhang, Wenyu Han, Xiaoyu Hong, Yifan Wang, Hong Qin, Shutian Wang, Qiaoyu Zhao, Yalei Wang, Yong Ping Yang, Kaijian Chen, Wei Zheng, Liangliang Kong, , Yao Cong

This study uses cryo-EM to reveal conformational dynamics of SARS-CoV-2 spike trimer in complex with ACE2, showing how ACE2 binding triggers structural changes and enhanced infectivity.

Science Advances · Dec 4, 2020Peer-reviewedMolecular Biology