Author

Zhanyu Ding

Chinese Academy of SciencesORCID 0000-0002-8136-2243Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Yanxing WangiD· 2 shared Cong XuiD· 1 shared Cong Yao· 1 shared Kaijian CheniD· 1 shared Qianqian SongiD· 1 shared Qiaoyu ZhaoiD· 1 shared Qin Hong· 1 shared Shaoning ZhangiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Yanxing WangORCID

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2 papers

Recent·Most cited

Mechanisms of Ub-independent ODC recognition and translocation by the 26S proteasome revealing proteasome's functional adaptability

Kaijian Chen, Yanxing Wang, Xingyan Ye, Zhanyu Ding, Xuyang Yuan, Cong Xu, Yue Yin, Yao Cong

This study reveals the mechanism by which the 26S proteasome recognizes and degrades ODC without ubiquitin, through cryo-EM structures showing dynamic interactions and translocation processes.

bioRxiv · Nov 15, 2025 · PreprintBiophysics

Development of immobilized antibody-based affinity grid strategy and application in on-grid purification of target proteins for high-resolution cryo-EM

Qiaoyu Zhao, Xiaoyu Hong, Yanxing Wang, Shaoning Zhang, Zhanyu Ding, Xueming Meng, Qianqian Song, Qin Hong, Wanying Jiang, Xiangyi Shi, Tianxun Cai, Cong Yao

The paper develops an immobilized antibody-based affinity grid strategy to improve cryo-EM sample preparation by enabling on-grid purification of target proteins and overcoming orientation issues.

bioRxiv · Jan 17, 2024 · PreprintMolecular Biology