Fangfang Wang

This study examines how altered medial olivocochlear (MOC) activity affects synaptic structure and function in the auditory brainstem using mouse models.

The paper introduces mito-SegEM, a method for efficiently mapping mitochondria in electron microscopy volumes using webKnossos, achieving accurate and efficient reconstruction across tissues.

The paper reconstructs neural circuitry in the mouse cochlea using electron microscopy, showing differences in efferent innervation of spiral ganglion neurons based on their synaptic connectivity with inner hair cells.

This study uses cryo-EM to reveal conformational dynamics of SARS-CoV-2 spike trimer in complex with ACE2, showing how ACE2 binding triggers structural changes and enhanced infectivity.