CRISPR-Cas supervises diverse anti-phage defense systems
Xian Shu, Rui Wang, Feiyue Cheng, Zhihua Li, Aici Wu, Qiong Xue, Chao Liu, Xifeng Cao, Yue Feng, Ming Li
This study shows CRISPR-Cas regulates diverse anti-phage systems via crlRNAs, balancing their expression to prevent autoimmunity and enhance anti-phage defense.
bioRxiv · Dec 27, 2024 · PreprintMicrobiology