Author

Xinlei Zeng

Chinese Academy of Medical Sciences & Peking Union Medical College

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Zilu YeiD· 3 shared Anjali SethiD· 1 shared Ariana E. ShannoniD· 1 shared Brian C. SearleiD· 1 shared Christian Michel BeuschiD· 1 shared Dong‐Jiunn Jeffery TruongiD· 1 shared Erwin M. SchoofiD· 1 shared Fabiana IzaguirreiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersSystems Biology

Zilu YeORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

End-to-end high-throughput single-cell proteomics via SPRINT and dual-spray LC-MS

Zhen Liu, Wenbo Dong, Lei Gu, Ruicheng Ge, Xinlei Zeng, Jingwen Deng, Haoran Zhang, Zilu Ye

The paper introduces an integrated workflow for high-throughput single-cell proteomics, achieving high throughput and protein identification using SPRINT and dual-spray LC-MS.

bioRxiv · Nov 3, 2025 · PreprintSystems Biology

Improving proteomic dynamic range with Multiple Accumulation Precursor Mass Spectrometry (MAP-MS)

Teeradon Phlairaharn, Ariana E. Shannon, Xinlei Zeng, Dong‐Jiunn Jeffery Truong, Erwin M. Schoof, Zilu Ye, Brian C. Searle

This study introduces MAP-MS, a method to improve proteomic dynamic range using Orbitrap mass spectrometers without hardware or software changes, achieving nearly 2x dynamic range with minimal impact.

bioRxiv · May 14, 2025 · PreprintBiochemistry

Global analysis of protein turnover dynamics in single cells

Pierre Sabatier, Maico Y. Lechner, Ulises H. Guzmán, Christian Michel Beusch, Xinlei Zeng, Longteng Wang, Fabiana Izaguirre, Anjali Seth, Olga Gritsenko, Sergey Rodin, Karl‐Henrik Grinnemo, Zilu Ye, Jesper Velgaard Olsen

This study introduces SC-pSILAC, a method to measure protein abundance and turnover in single cells, revealing differentiation-specific dynamics and cell-type markers in human iPSCs.

Cell · Apr 2, 2025Peer-reviewedSystems Biology