Fusogenic Structural Changes in Arenavirus Glycoproteins are Associated with Viroporin Activity
Y. B. Zhang, J. York, M. A. Brindley, J. H. Nunberg, G. B. Melikyan
The paper shows that conformational changes in arenavirus glycoproteins trigger virion membrane permeabilization and acidification before fusion, suggesting a viroporin-like activity that aids viral entry.
bioRxiv · Feb 20, 2023Microbiology