Author

Y. Ispolatov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Microbiology· 3 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Research Focus:ecology & biodiversity· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:E. coli· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1

Frequent Co-Authors

M. Doebeli· 4 shared K. Severinov· 3 shared I. N. Rubin· 2 shared N. Morozova· 2 shared A. Bukatin· 1 shared A. Kirillov· 1 shared A. Livenskyi· 1 shared A. Martynov· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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4 shared papersEvolutionary Biology

M. Doebeli

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Interference Requirements of Type III CRISPR-Cas Systems from Thermus thermophilus

K. Karneyeva, M. Kolesnik, A. Livenskyi, V. Zgoda, V. Zubarev, A. Trofimova, D. Artamonova, Y. Ispolatov, K. Severinov

This study investigates the interference requirements of Type III-A and III-B CRISPR-Cas systems from Thermus thermophilus, finding that target RNA abundance influences crRNA-target complementarity needed for interference.

bioRxiv · Sep 3, 2023 · PreprintMicrobiology

Adaptive diversification and niche packing on rugged fitness landscapes

I. N. Rubin, Y. Ispolatov, M. Doebeli

This study investigates how ruggedness in fitness landscapes affects adaptive diversification and stable diversity, finding that global carrying capacity shape, not local ruggedness, determines diversity outcomes.

bioRxiv · May 15, 2022Evolutionary Biology

Cells with Stochastically Increased Methyltransferase to Restriction Endonuclease Ratio Provide an Entry for Bacteriophage into Protected Cell Population

A. Kirillov, N. Morozova, V. Polinovaskaya, S. Smirnov, M. Khodorkovskii, L. Zeng, Y. Ispolatov, K. Severinov

The paper shows that altering the MTase to REase ratio in bacterial cells affects phage infection resistance, with higher ratios correlating with increased susceptibility.

bioRxiv · Mar 28, 2022Microbiology

Ecological diversity exceeds evolutionary diversity in model ecosystems

I. N. Rubin, Y. Ispolatov, M. Doebeli

The paper compares ecological diversity in randomly assembled communities to evolutionary diversity in ESSs, finding that ecological diversity can exceed evolutionary diversity under certain conditions.

bioRxiv · Mar 24, 2022 · PreprintEcology

Long-Term Persistence of Plasmids Targeted by CRISPR Interference in Bacterial Populations

V. Mamontov, A. Martynov, N. Morozova, A. Bukatin, D. B. Staroverov, K. A. Lukyanov, Y. Ispolatov, E. Semenova, K. Severinov

The paper shows plasmids can persist in E. coli under continuous CRISPR targeting without genetic changes, due to stochastic processes and plasmid replication dynamics.

bioRxiv · Apr 3, 2021 · PreprintMicrobiology

Boom-bust population dynamics can increase diversity in evolving competitive communities

M. Doebeli, E. C. Jaque, Y. Ispolatov

This study shows boom-bust population dynamics can increase diversity in competitive communities by allowing desynchronized species cycles.

bioRxiv · Nov 30, 2020Evolutionary Biology

Evolution of diversity in metabolic strategies

R. A. Caetano, Y. Ispolatov, M. Doebeli

The paper shows that non-linear physiological tradeoffs limit species diversity, while linear tradeoffs allow for high diversity in consumer-resource models.

bioRxiv · Oct 20, 2020Evolutionary Biology