N. Morozova

Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection

The paper shows that viral proteins activate PARIS-mediated tRNA degradation, and viral tRNAs rescue infection by preventing cleavage.

Cells with Stochastically Increased Methyltransferase to Restriction Endonuclease Ratio Provide an Entry for Bacteriophage into Protected Cell Population

The paper shows that altering the MTase to REase ratio in bacterial cells affects phage infection resistance, with higher ratios correlating with increased susceptibility.

tRNA anticodon cleavage by target-activated CRISPR-Cas13a effector

The paper shows that Cas13a cleaves tRNA anticodons to induce bacterial dormancy and activates toxin-antitoxin modules for mRNA and rRNA cleavage.

Long-Term Persistence of Plasmids Targeted by CRISPR Interference in Bacterial Populations

The paper shows plasmids can persist in E. coli under continuous CRISPR targeting without genetic changes, due to stochastic processes and plasmid replication dynamics.

Detection of Spacer Precursors Formed In Vivo During Primed CRISPR Adaptation

The paper develops a method to detect spacer precursors formed during primed CRISPR adaptation in vivo and identifies their structural and functional characteristics.

Mathematical Modeling Reveals the Factors Involved in the Phenomena of Cancer Stem Cells Stabilization

The paper develops a mathematical model to explain the stabilization of cancer stem cell populations and identifies key factors influencing this phenomenon.