Cells with Stochastically Increased Methyltransferase to Restriction Endonuclease Ratio Provide an Entry for Bacteriophage into Protected Cell Population
A. Kirillov, N. Morozova, V. Polinovaskaya, S. Smirnov, M. Khodorkovskii, L. Zeng, Y. Ispolatov, K. Severinov
The paper shows that altering the MTase to REase ratio in bacterial cells affects phage infection resistance, with higher ratios correlating with increased susceptibility.
bioRxiv · Mar 28, 2022Microbiology