Author

Y. Kosaka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

E. F. Lind· 2 shared J. L. Coy· 2 shared P. A. Flynn· 2 shared A. Agarwal· 1 shared C. Loo· 1 shared D. Arima· 1 shared H. J. Cho· 1 shared J. S. Mulkey· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

E. F. Lind

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Leukemic mutation FLT3-ITD is retained in dendritic cells and disrupts their homeostasis leading to expanded Th17 frequency

P. A. Flynn, M. D. Long, Y. Kosaka, J. S. Mulkey, J. L. Coy, A. Agarwal, E. F. Lind

This study shows FLT3-ITD mutations in AML retain in dendritic cells, altering their phenotype and increasing Th17 T cell frequency.

bioRxiv · Sep 19, 2023Immunology

Morphological variation and phylogeny of Karenia selliformis (Gymnodiniales, Dinophyceae) in an intensive cold-water algal bloom in eastern Hokkaido, Japan in September-November 2021

M. Iwataki, W. M. Lum, K. Kuwata, K. Takahashi, D. Arima, T. Kuribayashi, Y. Kosaka, N. Hasegawa, T. Watanabe, T. Shikata, T. Isada, T. Y. Orlova, S. Sakamoto

The paper examines the morphology and phylogeny of Karenia selliformis and other co-occurred dinoflagellates in a harmful algal bloom in eastern Hokkaido, Japan, identifying morphological variation and genetic similarity to a bloom in Kamchatka, Russia.

bioRxiv · Dec 13, 2021Ecology

BET inhibitors synergize with anti-PD1 by rescuing TCF1+ progenitor exhausted CD8+ T cells in Acute Myeloid Leukemia

K. A. Romine, H. J. Cho, Y. Kosaka, K. H. Byrd, J. L. Coy, P. A. Flynn, M. T. Newman, C. Loo, J. Scott, E. F. Lind

This study shows BET inhibitors enhance anti-PD1 therapy by reversing T cell exhaustion in AML, increasing CD8+ T cell function and reducing leukemia cells.

bioRxiv · Aug 4, 2021 · PreprintCancer Biology