H. J. Cho

A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma

The paper characterizes immune microenvironment dysregulation in multiple myeloma using single-cell data and links it to disease progression and patient outcomes.

The VR Billboard Paradigm: Using VR and Eye-tracking to Examine the Exposure-Reception-Retention Link in Realistic Communication Environments

This paper uses VR and eye-tracking to measure exposure, reception, and retention of messages in realistic environments, showing that attention manipulation affects gaze and memory.

Isolation disrupts social interactions and destabilizes brain development in bumblebees

This study shows that social isolation in early life disrupts brain development and gene expression in bumblebees, while limited social experience preserves typical patterns.

BET inhibitors synergize with anti-PD1 by rescuing TCF1+ progenitor exhausted CD8+ T cells in Acute Myeloid Leukemia

This study shows BET inhibitors enhance anti-PD1 therapy by reversing T cell exhaustion in AML, increasing CD8+ T cell function and reducing leukemia cells.

Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge

This study identifies clonal subpopulations in glioblastoma core and edge lesions and shows that NAD+ depletion via CD38 inhibition reduces tumor edge formation.

Tumor Edge-to-Core Transition Promotes Malignancy in Primary-to-Recurrent Glioblastoma Progression in a PLAGL1/CD109-mediated mechanism

The paper identifies a CD133down/CD109up signature associated with poor prognosis in glioblastoma recurrence and shows PLAGL1 mediates tumor progression through CD109 regulation.

Patient Similarity Network of Multiple Myeloma Identifies Patient Sub-groups with Distinct Genetic and Clinical Features

The paper introduces MM-PSN, a multi-omics patient similarity network for Multiple Myeloma, identifying three broad groups and twelve sub-groups with distinct genetic and clinical features.