Disrupting β-catenin dependent Wnt signaling activates an invasive gene program predictive of colon cancer progression
G. T. Chen, D. F. Tifrea, R. Murad, Y. Lyou, A. Mortazavi, R. A. Edwards, M. L. Waterman
This study shows that reducing Wnt signaling in colon cancer cells increases their invasiveness and identifies gene markers predictive of poor patient outcomes.
bioRxiv · Jul 16, 2019Cancer Biology