A. Mortazavi

Size-Dependent Mechanoadaptation Enables Migration with Oversized Parasitic Cargo

The paper investigates how cells adapt to transport oversized parasitic cargo by reprogramming mechanical forces and subcellular architecture during migration.

Traction Force Microscopy with DNA FluoroCubes

This paper introduces FluoroCubes as fiducial markers for traction force microscopy, enabling high-resolution force mapping with improved sensitivity and compatibility with TIRF microscopy.

Transcriptome analysis of heterogeneity in mouse model of metastatic breast cancer

The paper analyzes tumor heterogeneity and organ tropism in a mouse model of metastatic breast cancer using bulk and single-cell RNA-seq.

Multiple mechanisms of photoreceptor spectral tuning following loss of UV color vision in Heliconius butterflies

The paper examines how the loss of the UV2 photoreceptor in Heliconius butterflies has led to multiple spectral tuning mechanisms in their visual systems.

Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave

The paper depletes adult microglia using CSF1R inhibition and shows that subventricular zone/white matter myeloid cells dynamically repopulate the brain, exhibiting distinct phenotypes from endogenous microglia.

Transcriptome-Wide Combinatorial RNA Structure Probing in Living Cells

This study introduces icLASER, a method to map RNA solvent accessibility transcriptome-wide, and combines it with icSHAPE to predict RNA-protein interactions and polyadenylation sites.

Disrupting β-catenin dependent Wnt signaling activates an invasive gene program predictive of colon cancer progression

This study shows that reducing Wnt signaling in colon cancer cells increases their invasiveness and identifies gene markers predictive of poor patient outcomes.