Author

G. T. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. L. Waterman· 2 shared A. Mortazavi· 1 shared A. P. Lee· 1 shared A. Tankazyan· 1 shared C. C. Hughes· 1 shared D. A. Lawson· 1 shared D. F. Tifrea· 1 shared D. Zhao· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

M. L. Waterman

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Author profile →

2 papers

Recent·Most cited

An In Vitro Vascularized Micro-Tumor Model of Human Colorectal Cancer Recapitulates In Vivo Drug Responses

S. J. Hachey, S. Movsesyan, Q. H. Nguyen, G. Burton-Sojo, A. Tankazyan, J. Wu, T. Hoang, M. M. Hatch, D. Zhao, E. Celaya, S. Gomez, G. T. Chen, R. T. Davis, K. Nee, N. Pervolarakis, , C. C. Hughes

This paper validates a vascularized micro-tumor model for colorectal cancer that better replicates in vivo drug responses than traditional 2D or 3D models.

bioRxiv · Mar 3, 2020Cancer Biology

Disrupting β-catenin dependent Wnt signaling activates an invasive gene program predictive of colon cancer progression

G. T. Chen, D. F. Tifrea, R. Murad, Y. Lyou, A. Mortazavi, R. A. Edwards, M. L. Waterman

This study shows that reducing Wnt signaling in colon cancer cells increases their invasiveness and identifies gene markers predictive of poor patient outcomes.

bioRxiv · Jul 16, 2019Cancer Biology