Author

Y. M. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Bleyer· 1 shared A. Puri· 1 shared A. Raybuck· 1 shared B. G. Johnson· 1 shared B. M. Little· 1 shared C. Gu· 1 shared C. Li· 1 shared C. X. He· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. J. Bleyer

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Author profile →

3 papers

Recent·Most cited

The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness

H. Zeng, X. Zhu, Y. Wu, Y. Li, X. Zhou, J. Watzlawik, Y. M. Chen, A. Raybuck, D. Billadeau, V. Shapiro, W. Springer, J. Sun, M. R. Boothby

This study shows that Rag-GTPases regulate B cell metabolism and immunity by restraining TFEB/TFE3 to maintain mitochondrial fitness and support T-independent humoral immunity.

bioRxiv · Feb 26, 2024Immunology

MANF stimulates autophagy and restores mitochondrial homeostasis to treat toxic proteinopathy

Y. Kim, C. Li, C. Gu, E. Tycksen, A. Puri, T. A. Pietka, J. Sivapackiam, Y. Fang, K. Kidd, S.-J. Park, B. G. Johnson, S. Kmoch, J. S. Duffield, A. J. Bleyer, M. E. Jackrel, , Y. M. Chen

This study shows that MANF improves autophagy and mitochondrial function in a mouse model of ADTKD-UMOD, offering a potential therapy for proteinopathies.

bioRxiv · Jan 10, 2023 · PreprintCell Biology

Stratified Random Sampling Methodology for Observing Community Mask Use within Indoor Settings: Results from Louisville, Kentucky during the COVID-19 Pandemic

S. M. KARIMI, S. S. Salunkhe, K. B. White, B. M. Little, W. P. M. McKinney, R. M. Mitra, Y. M. Chen, E. R. Adkins, J. A. Barclay, E. M. Ezekekwu, C. X. He, D. M. Hurst, M. M. M. Popescu, D. N. Swinney, D. A. Johnson, , N. R. DuPre

This study used stratified random sampling to observe mask use in indoor public areas during the COVID-19 pandemic, finding high prevalence but significant disparities in proper use.

bioRxiv · Feb 25, 2021 · PreprintScientific Communication & Education