Spatio-temporal control of DNA replication by the pneumococcal cell cycle regulator CcrZ
C. Gallay, S. Sanselicio, M. E. Anderson, Y. M. Soh, X. Liu, G. A. Stamsas, S. Pelliciari, R. van Raaphorst, J. Denereaz, M. Kjos, H. Murray, S. Gruber, A. D. Grossman, J.-W. Veening
This study identifies CcrZ as a regulator that couples DNA replication with cell division in pneumococci by controlling DnaA activity, ensuring proper chromosome inheritance.
bioRxiv · Jun 2, 2021Microbiology