Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
12 papers
Recent·Most cited
T. Yang, I. Chandel, M. Gonzales, H. Okuma, S. J. Prouty, S. Zarei, S. Joseph, K. W. Garringer, S. Ocampo Landa, T. Yonekawa, A. S. Walimbe, D. P. Venzke, M. E. Anderson, J. M. Hord, K. P. Campbell
The paper identifies a shorter matriglycan on dystroglycan that maintains neuromuscular function in adult mice and protects skeletal muscle from damage.
bioRxiv · Dec 20, 2023 · PreprintBiochemistry
Y. Wu, Q. Wang, J. Granger, O. E. Reyes Gaido, E. N. Aguilar, A. Ludwig, A. Moroni, M. A. Bianchet, M. E. Anderson
The paper identifies a conserved motif in HCN4 channels that mediates heat sensing and modulates heart rate responses to thermal energy.
bioRxiv · Sep 2, 2023 · PreprintPhysiology
H. Okuma, J. M. Hord, I. Chandel, M. E. Anderson, D. Venzke, A. S. Walimbe, S. Joseph, Z. Gastel, Y. Hara, F. Saito, K. Matsumura, K. P. Campbell
This study shows that the N-terminal domain of dystroglycan is required for LARGE1 to extend matriglycan to its full length, preventing muscular dystrophy.
eLife · Feb 1, 2023Peer-reviewedBiochemistry
O. E. Reyes Gaido, K. L. Schole, M. E. Anderson, E. D. Luczak
The paper identifies genetic modifiers of Ca2+-mediated cell death through a genome-wide CRISPR screen in human cells exposed to ionomycin.
bioRxiv · Jan 13, 2023 · PreprintCell Biology
S. Joseph, N. J. Schnicker, Z. Xu, T. Yang, J. Hopkins, M. Watkins, S. Chakravarthy, O. Davulcu, M. E. Anderson, D. Venzke, K. P. Campbell
The paper determines the cryo-EM structure of LARGE1 and shows it functions as a dimer to processively polymerize matriglycan on dystroglycan using alternating active sites.
bioRxiv · May 12, 2022Biochemistry
T. Yonekawa, A. J. Rauckhorst, S. Y. El-Hattab, M. A. Cuellar, D. Venzke, M. E. Anderson, H. Okuma, A. D. Pewa, E. B. Taylor, K. P. Campbell
This study shows that gene transfer using AAV2/9 CMV Large1 in older myd mice with severe muscular dystrophy restores muscle function and significantly improves survival.
bioRxiv · Oct 28, 2021Physiology
C. Gallay, S. Sanselicio, M. E. Anderson, Y. M. Soh, X. Liu, G. A. Stamsas, S. Pelliciari, R. van Raaphorst, J. Denereaz, M. Kjos, H. Murray, S. Gruber, A. D. Grossman, J.-W. Veening
This study identifies CcrZ as a regulator that couples DNA replication with cell division in pneumococci by controlling DnaA activity, ensuring proper chromosome inheritance.
bioRxiv · Jun 2, 2021Microbiology
M. E. Anderson, J. L. Smith, A. D. Grossman
The paper identifies multiple mechanisms by which cells regulate DNA replication in Bacillus subtilis, including reducing initiation and enhancing elongation to overcome over-initiation caused by dnaA1 mutation.
bioRxiv · May 6, 2021Microbiology
G. K. Muller, J. Song, V. Jani, Y. Wu, M. E. Anderson, D. A. Kass
This paper investigates how PDE1 inhibition increases cardiac contractility by enhancing Cav1.2 channel conductance through PKA, with less intracellular calcium rise and arrhythmia compared to beta-ARs or PDE3i.
bioRxiv · Nov 5, 2020Pharmacology & Toxicology
A. S. Walimbe, H. Okuma, S. Joseph, T. Yang, T. Yonekawa, J. M. Hord, D. Venzke, M. E. Anderson, S. Torelli, A. Manzur, M. Devereaux, M. Cuellar, S. Prouty, S. Ocampo Landa, L. Yu, , K. P. Campbell
This study shows that POMK phosphorylates core M3 to enable LARGE to elongate matriglycan on dystroglycan, preventing muscular dystrophy.
bioRxiv · Apr 6, 2020Biochemistry
Q. Wang, E. O. Hernandez-Ochoa, M. C. Viswanathan, I. D. Blum, J. M. Granger, K. R. Murphy, A.-C. Wei, S. Aja, N. Liu, C. M. Antonescu, L. D. Florea, C. C. Talbot, D. Mohr, K. R. Wagner, S. Regot, , M. E. Anderson
This study shows CaMKII oxidation by ROS evolved in vertebrates to enhance performance but increased disease risk.
bioRxiv · Sep 13, 2019Evolutionary Biology