A conserved antigen induces respiratory Th17-mediated serotype-independent protection against pneumococcal superinfection
X. Liu, L. Van Maele, L. Matarazzo, D. Soulard, V. Alves Duarte da Silva, V. de Bakker, J. Denereaz, F. P. Bock, M. Taschner, S. Gruber, V. Nizet, J.-C. Sirard, J.-W. Veening
The paper identifies a conserved antigen, LafB, that provides serotype-independent protection against pneumococcal superinfection via Th17 cells, independent of antibodies.
bioRxiv · Jul 7, 2023 · PreprintMicrobiology