Mechanical Stretch Kills Transformed Cancer Cells
A. Tijore, M. Yao, Y.-H. Wang, Y. Nematbakhsh, A. Hariharan, C. T. Lim, M. Sheetz
The paper shows that cyclic mechanical stretch induces apoptosis in transformed cancer cells but promotes growth in normal cells, with mechanoptosis driven by calcium influx and calpain activation.
bioRxiv · Dec 10, 2018 · PreprintCell Biology