Author

A. Tijore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Organism:human· 1

Frequent Co-Authors

A. Hariharan· 2 shared M. Sheetz· 2 shared M. Yao· 2 shared C. A. Z. Chew· 1 shared C. T. Lim· 1 shared F. Margadant· 1 shared G. K. Bonney· 1 shared S. Powell· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

A. Hariharan

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Author profile →

2 papers

Recent·Most cited

Ultrasound-mediated mechanical forces selectively kill tumor cells

A. Tijore, F. Margadant, M. Yao, A. Hariharan, C. A. Z. Chew, S. Powell, G. K. Bonney, M. Sheetz

This paper shows low-frequency ultrasound selectively kills tumor cells via a calpain-dependent mitochondrial pathway involving Piezo1 channels, with minimal damage to normal cells in animal models and patient-derived organoids.

bioRxiv · Oct 9, 2020 · PreprintCancer Biology

Mechanical Stretch Kills Transformed Cancer Cells

A. Tijore, M. Yao, Y.-H. Wang, Y. Nematbakhsh, A. Hariharan, C. T. Lim, M. Sheetz

The paper shows that cyclic mechanical stretch induces apoptosis in transformed cancer cells but promotes growth in normal cells, with mechanoptosis driven by calcium influx and calpain activation.

bioRxiv · Dec 10, 2018 · PreprintCell Biology