Author

Y. O. Alexandre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

S. N. Mueller· 2 shared A. E. Denton· 1 shared A. L. Fletcher· 1 shared B. Ludewig· 1 shared C. Perez Shibayama· 1 shared D. Roberts· 1 shared E. Dutton· 1 shared G. T. Belz· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

S. N. Mueller

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Author profile →

3 papers

Recent·Most cited

The transcription factor SpiB regulates Fibroblastic Reticular Cell network and CD8+ T cell responses in lymph nodes

H. L. Horsnell, W. H. Cao, G. T. Belz, S. N. Mueller, Y. O. Alexandre

This study shows that SpiB regulates FRC network structure and CD8+ T cell responses in lymph nodes by affecting FRC function and immune coordination.

bioRxiv · Oct 12, 2023Immunology

Fibroblastic reticular cells provide a supportive niche for lymph node-resident macrophages

J. D'Rozario, K. Knoblich, M. Luetge, C. Perez Shibayama, H.-W. Cheng, Y. O. Alexandre, D. Roberts, J. Campos, J. Astarita, E. Dutton, M. Suliman, A. E. Denton, S. J. Turley, R. L. Boyd, S. Mueller, , A. L. Fletcher

This study identifies fibroblastic reticular cells (FRCs) as essential for supporting lymph node-resident macrophages through CSF1 and CSF1R signaling.

bioRxiv · Nov 24, 2021Immunology

Systemic inflammation suppresses lymphoid tissue remodeling and B cell immunity during concomitant local infection

Y. O. Alexandre, S. Devi, S. L. Park, L. K. Mackay, W. R. Heath, S. N. Mueller

This study shows that systemic inflammation during local infection suppresses lymphoid tissue remodeling and B cell immunity by causing lymphopenia and impairing dLN function.

bioRxiv · Jul 6, 2020Immunology