Author

S. L. Park

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Approach:biophysical modeling· 2 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

M. Peter· 2 shared W. I. Mohamed· 2 shared A. A. Franke· 1 shared A. Leitner· 1 shared B. F. Darst· 1 shared C. A. Haiman· 1 shared C. Kearny· 1 shared D. Boehringer· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

M. Peter

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The hGID GID4 E3 ubiquitin ligase complex targets ARHGAP11A to regulate cell migration

H. Bagci, M. Winkler, F. Uliana, J. Boulais, W. I. Mohamed, S. L. Park, J.-F. Cote, M. Peter

This study identifies GID4 as a substrate receptor of the hGID E3 ligase complex that targets ARHGAP11A for degradation, thereby regulating cell migration.

bioRxiv · Jul 20, 2023Biochemistry

The human GID complex engages two independent modules for substrate recruitment

M. Peter, W. I. Mohamed, S. L. Park, J. Rabl, A. Leitner, D. Boehringer

This study identifies two distinct modules in the human GID complex for substrate recruitment, revealing different roles for WDR26 and GID4 in ubiquitination and substrate recognition.

The EMBO Reports · Oct 14, 2021Peer-reviewedBiochemistry

Genome-wide Association Study of Pancreatic Fat: The Multiethnic Cohort Adiposity Phenotype Study

S. Streicher, U. Lim, S. L. Park, Y. Li, X. Sheng, V. Hom, L. Xia, L. Pooler, J. Shepherd, L. W. Loo, B. F. Darst, H. M. Highland, L. M. Polfus, D. Bogumil, T. Ernst, , L. Le Marchand

This study identifies two genetic variants associated with pancreatic fat content and suggests a potential link between pancreatic fat and type 2 diabetes.

bioRxiv · Mar 23, 2021Cell Biology

Systemic inflammation suppresses lymphoid tissue remodeling and B cell immunity during concomitant local infection

Y. O. Alexandre, S. Devi, S. L. Park, L. K. Mackay, W. R. Heath, S. N. Mueller

This study shows that systemic inflammation during local infection suppresses lymphoid tissue remodeling and B cell immunity by causing lymphopenia and impairing dLN function.

bioRxiv · Jul 6, 2020Immunology

Naringenin as an antibacterial reagent controlling of biofilm formation and fatty acid metabolism in MRSA

H.-S. Song, S. K. Bhatia, R. Gurav, T.-R. Choi, H. J. Kim, Y.-L. Park, Y.-H. Han, J. Y. Park, S. m. Lee, S. L. Park, H. S. Lee, W. Kim, Y.-G. Kim, Y.-H. Yang

This study identifies naringenin as an antibacterial agent that reduces biofilm formation and fatty acid secretion in MRSA and shows synergy with oxacillin.

bioRxiv · Mar 8, 2020 · PreprintMicrobiology

PTPN2 deletion in T cells promotes anti-tumour immunity and CAR T cell efficacy in solid tumours

F. Wiede, K.-H. Lu, X. Du, S. Liang, K. Hochheiser, G. Dodd, P. Goh, C. Kearny, D. Meyran, P. Beavis, M. Henderson, S. L. Park, J. Waithman, S. Zhang, Z.-Y. Zhang, , T. Tiganis

This study shows that deleting PTPN2 in T cells improves anti-tumour immunity and CAR T cell effectiveness against solid tumours.

bioRxiv · Sep 5, 2019Immunology