Y. S. Morita

This study shows that lipoarabinomannan (LAM) regulates septation in Mycobacterium smegmatis, affecting cell envelope integrity and septal placement.

The paper identifies tuberculostearic acid (TBSA) as a key lipid controlled by the gene cfa, which regulates membrane compartmentalization in Mycobacterium smegmatis.

This study shows that mycobacteria rapidly modify phosphatidylinositol mannosides (PIMs) by adding an inositol acyl chain in response to membrane fluidization, enhancing resistance to membrane stress.

This study identifies PgfA as a periplasmic protein essential for asymmetric polar growth in mycobacteria by coordinating lipid trafficking and cell wall synthesis.

This paper identifies the conserved intracellular membrane domain (IMD) in Mycobacterium tuberculosis, showing it is a specialized compartment for synthesizing virulence-related lipids.

This study investigates the role of RodA in mycobacterial cell wall synthesis under damage, showing its non-redundant function in spatially flexible peptidoglycan assembly and stress response.

The paper uses fluorescence imaging to verify and discover new proteins associated with the intracellular membrane domain in Mycobacterium smegmatis.

The paper shows that in Mycobacterium smegmatis, peptidoglycan precursors are synthesized in distinct plasma membrane domains that are separate from sites of cell wall assembly, and this partitioning is essential for ordered synthesis.

This study shows that LmeA stabilizes MptA and maintains LM levels under stress, ensuring cell envelope integrity.

This study identifies MenG as an essential enzyme for menaquinone homeostasis in Mycobacterium smegmatis, showing its association with the intracellular membrane domain and its role in regulating menaquinone levels.

The paper investigates peptidoglycan precursor synthesis in mycobacteria, showing that sidewall synthesis responds to cell wall damage while polar synthesis is linked to elongation.