Author

T. van Eeuwen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:cryo-EM· 2 Research Focus:cell type annotation· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Organism:multiple species· 1

Frequent Co-Authors

A. Sali· 2 shared B. T. Chait· 2 shared J. Fernandez-Martinez· 2 shared M. P. Rout· 2 shared A. M. Gautreau· 1 shared A. Mazur· 1 shared A. Zimmet· 1 shared B. A. Garcia· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

A. Sali

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Author profile →

4 papers

Recent·Most cited

The Molecular Architecture of the Nuclear Basket

D. Singh, N. Soni, J. Hutchings, I. Echeverria, F. Shaikh, M. Duquette, S. Suslov, Z. Li, T. van Eeuwen, K. Molloy, Y. Shi, J. Wang, Q. Guo, B. T. Chait, J. Fernandez-Martinez, , E. Villa

This study uses structural biology to reveal the architecture of the nuclear basket in yeast and mammals, showing how Mlp/Tpr proteins form its structural components.

bioRxiv · Mar 27, 2024Biophysics

Dynamic molecular mechanism of the nuclear pore complex permeability barrier

T. Kozai, J. Fernandez-Martinez, T. van Eeuwen, P. Gallardo, L. E. Kapinos, A. Mazur, W. Zhang, J. Tempkin, R. Panatala, M. Delgado-Izquierdo, B. Raveh, A. Sali, B. T. Chait, L. M. Veenhoff, M. P. Rout, R. Y. H. Lim

The paper investigates the dynamic behavior of the nuclear pore complex permeability barrier in yeast, showing it functions as a dynamic polymer brush rather than a phase-separated condensate.

bioRxiv · Mar 31, 2023 · PreprintBiophysics

Molecular mechanism of Arp2/3 complex inhibition by Arpin

F. E. Fregoso, T. van Eeuwen, G. Simanov, G. Rebowski, M. Boczkowska, A. Zimmet, A. M. Gautreau, R. Dominguez

This study determines the cryo-EM structure of Arpin bound to Arp2/3 complex and identifies sequence differences in the C-helix that distinguish inhibition from activation.

bioRxiv · Oct 30, 2021Biochemistry

Structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in Nucleotide Excision Repair

T. van Eeuwen, Y. Shim, H. J. Kim, T. Zhao, S. Basu, C. D. Kaplan, B. A. Garcia, J. H. Min, K. Murakami

The paper presents a cryo-EM structure of an NER initiation complex involving Rad4-Rad23-Rad33 and TFIIH bound to a DNA lesion, revealing DNA unwinding and translocation mechanisms.

bioRxiv · Jan 14, 2021Biophysics