An infectivity-enhancing site on the SARS-CoV-2 spike protein is targeted by COVID-19 patient antibodies
Y. Liu, W. T. Soh, A. Tada, A. Arakawa, S. Matsuoka, E. E. Nakayama, S. Li, C. Ono, S. Torii, K. Kishida, H. Jin, W. Nakai, N. Arase, A. Nakagawa, Y. Shindo, , H. Arase
This study identifies an NTD site on SARS-CoV-2 spike protein that enhances infectivity when targeted by antibodies, and finds these antibodies are present in hospitalized patients and some uninfected donors.
bioRxiv · Dec 18, 2020Microbiology