Y. Soeda

Intracellular Tau Fragment Droplets Serve as Seeds for Tau Fibrils

This study shows that intracellular tau droplets form via microtubule collapse and act as seeds for tau fibrils, linking droplet formation to neurofibrillary tangle development in Alzheimer's disease.

Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool.

This paper introduces OptoTau, an optogenetic tool that induces different tau aggregation forms in Neuro2a cells based on blue light exposure patterns.