T. Takahashi

Discovery of anti-SARS-CoV-2 S2 protein antibody CV804 with broad-spectrum reactivity with various beta coronaviruses and analysis of its pharmacological properties in vitro and in vivo

This study identifies an antibody, CV804, that targets the conserved S2 domain of coronaviruses and shows broad cross-reactivity and ADCC activity against SARS-CoV-2 and related viruses.

Nutritional characterisation and seasonal variation of goat forages in Central Malawi

This study characterizes the nutritional profile and seasonal variation of goat forages in Central Malawi, finding that forage nutrition and availability are highest in the wet season and decline in the dry season, creating a seasonal nutrition gap.

Opportunities to improve goat production and food security in Botswana through forage nutrition and the use of supplemental feeds

This study evaluates feed quality and supplementation strategies for goats in Botswana to improve nutrition and health, finding significant seasonal and soil-type variations in feed nutrition and higher supplement consumption during the dry season.

Thermospermine is an evolutionarily ancestral phytohormone required for organ development and stress responses in the basal land plant Marchantia polymorpha

This study identifies thermospermine as a key phytohormone in liverworts, showing its role in organ development and stress responses, with implications for evolutionary plant biology.

Overexpression of NIMA-related kinase suppresses cell proliferation and tip growth in a liverwort Marchantia polymorpha

This study shows that overexpressing MpNEK1 in liverwort inhibits cell proliferation and growth, leading to lethality, suggesting a conserved role for NEKs in cell division across species.

Golgi retention and oncogenic KIT signaling via PLCγ2-PKD2-PI4KIIIβ activation in GIST cells

This study identifies the molecular mechanisms by which mutant KIT remains in the Golgi and activates oncogenic signaling in GIST cells.

RNA processing/modifying enzymes play key roles in the response to thermospermine in Arabidopsis thaliana

The paper identifies four genes involved in RNA processing and modification that modulate thermospermine's effect on xylem differentiation in Arabidopsis.

Plant specific armadillo repeat kinesin directs organelle transport and microtubule convergence to promote tip growth

This study identifies MpARK, a plant-specific kinesin, as essential for organelle transport and microtubule convergence in tip-growing rhizoids, supporting plant anchorage and growth.

Engineering of an electrically charged hydrogel implanted into a traumatic brain injury model for stepwise neuronal tissue reconstruction

The paper describes a two-step method using charged hydrogels and neural stem cell injection to promote brain tissue reconstruction after traumatic injury.

Acoustic frequency-dependent physical mechanism of sub-MHz ultrasound neurostimulation

This study investigates how different acoustic frequencies affect ultrasound neuromodulation by examining cavitation and radiation forces in cultured rat cortical cells.

Evaluation of the Efficacy and Safety of a Clinical Grade Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Patch: A Pre-Clinical Study

This pre-clinical study evaluates the safety and efficacy of clinical-grade human iPSC-derived cardiomyocyte patches in treating heart failure, showing improved cardiac function and no adverse effects.

Crosstalk between repair pathways elicits Double-Strand Breaks in alkylated DNA: implications for the action of temozolomide

This study investigates how temozolomide induces DNA double-strand breaks through crosstalk between repair pathways in Xenopus egg extracts.

A new method of Bayesian causal inference in non-stationary environments

This paper introduces an extended Bayesian inference method that improves causal inference in non-stationary environments by balancing learning and forgetting effects.

Extended Bayesian inference incorporating symmetry bias

This paper introduces a Bayesian inference method that incorporates symmetry bias to enable flexible inference and learning in changing situations.

Correlation Detection with and without the Theories of Conditionals: A model update of Hattori & Oaksford (2007)

This paper updates a causal induction model by introducing pARIs, showing it matches the descriptive adequacy of the DFH model while addressing simulation issues.

A regulatory module controlling stress-induced cell cycle arrest in Arabidopsis

This study identifies ANAC044 and ANAC085 as key regulators of DNA damage-induced G2 arrest in Arabidopsis, showing their role in enhancing Rep-MYB accumulation and cell cycle arrest under specific stress conditions.