N. Kato

Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool.

This paper introduces OptoTau, an optogenetic tool that induces different tau aggregation forms in Neuro2a cells based on blue light exposure patterns.

Downstream metabolites of (+)-cis-12-oxo-phytodienoic acid function as noncanonical bioactive jasmonates in Arabidopsis thaliana.

The paper identifies downstream metabolites of cis-OPDA as noncanonical bioactive jasmonates in Arabidopsis thaliana that function independently of the JA-Ile-COI1-JAZ signaling pathway.

PNPO-PLP Axis Senses Prolonged Hypoxia by Regulating Lysosomal Activity

The paper identifies the PNPO-PLP axis as a mechanism for sensing prolonged hypoxia by regulating lysosomal activity in macrophages, leading to altered inflammatory responses.

Isolation of gametes and zygotes from Setaria viridis

This paper describes a method to isolate gametes, zygotes, and embryos from Setaria viridis for studying fertilization and development in angiosperms.

The Conserved Colletotrichum spp. Effector CEC3 Induces Nuclear Expansion and Cell Death in Plants

This study identifies CEC3 as a conserved effector in Colletotrichum fungi that induces nuclear expansion and cell death in plants, supporting its role in the hemibiotrophic lifestyle.

Molecular basis for two stereoselective Diels-Alderases that produce decalin skeletons

This study determines the molecular mechanisms of two Diels-Alderases that produce enantiomeric decalin scaffolds through structural and computational analyses.

Whole-genome sequence analysis of mutations in rice plants regenerated from zygotes, mature embryos, and immature embryos

The paper analyzes whole-genome sequences of rice plants regenerated from different embryonic sources to assess somaclonal variation and mutation rates.

Orthosteric-allosteric dual inhibitors of PfHT1 as selective anti-malarial agents

This paper develops dual orthosteric-allosteric inhibitors of PfHT1 that selectively target malaria parasites over human cells, showing potent activity against multidrug-resistant strains.

The CDK inhibitor SIAMESE targets both CDKA;1 and CDKB1 complexes to establish endoreplication in trichomes

The paper identifies that SIAMESE inhibits both CDKA;1 and CDKB1 complexes to promote endoreplication in Arabidopsis trichomes and interacts with CYCA2;3 via SIM Motif A.

High-level expression of STING restricts susceptibility to HBV by mediating type III IFN induction

The paper shows that high STING expression in hepatocytes reduces HBV susceptibility by inducing type III IFN and IL-6.