Y. Tao

This study determines the cryo-EM structure of a novel α-synuclein fibril formed by the E46K mutation, showing structural changes and altered stability compared to wild-type fibrils.

This study identifies miR476a/RFL as a regulator of adventitious root formation in poplar through mitochondrial homeostasis and auxin pathway modulation.

This study develops a computational framework to predict cancer progression using mutator phenotypes derived from tumor phylogenies, showing improved predictive power over traditional clinical and driver-centric features.

This study identifies genetic lesions in oxidative respiration and iron acquisition pathways in small-colony variant (SCV) clinical isolates of Gram-negative bacteria, showing their role in virulence attenuation and persistence in vivo.

The paper studies mutational meltdown in HeLa cancer cell populations, finding high rates of deleterious copy number variations and significant fitness reduction per mutation.

This study predicts the evolutionary pathway of norovirus escaping antibodies using a biophysical fitness model, validated by experimental evolution in bulk culture and microfluidics.