Author

Y.-M. Hu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. E. Moran· 2 shared Z. Xia· 2 shared A. Argulian· 1 shared A. Kardosh· 1 shared A. Patnaik· 1 shared B. Labadie· 1 shared C. Chen· 1 shared D. B. Sykes· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

A. E. Moran

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2 papers

Recent·Most cited

Androgen receptor activity inversely correlates with immune cell infiltration and immunotherapy response across multiple cancer lineages

Y.-M. Hu, F. Zhao, J. Graff, C. Chen, X. Zhao, G. V. Thomas, H. Wu, A. Kardosh, G. Mills, J. Alumkal, A. E. Moran, Z. Xia

The paper examines the relationship between androgen receptor activity and immune cell infiltration, showing that lower AR activity correlates with increased immune activity and better immunotherapy response across multiple cancers.

bioRxiv · May 8, 2024 · PreprintCancer Biology

Androgen blockade primes NLRP3 in macrophages to induce tumor phagocytosis

K. K. Chaudagar, R. Srikrishnan, S. Mei, T. Hirz, Y.-M. Hu, A. Argulian, B. Labadie, K. Desai, S. Grimaldo, D. Kahramangil, R. Nair, S. D Souza, D. Zhou, M. Li, F. Doughan, , A. Patnaik

This study shows that androgen blockade increases NLRP3 in macrophages, which when combined with NLRP3 agonist, enhances cancer cell phagocytosis and tumor control in a mouse model of prostate cancer.

bioRxiv · Sep 15, 2023 · PreprintCancer Biology