Chromosome segment scanning for gain- or loss-of-function screening (CHASING) and its application in metabolic engineering
Y. Xia, L. Sun, Z. Liang, Z. Han, J. Li, Y. Guo, P. Dong, Y.-X. Huo, S. Guo
The paper introduces CHASING, a method for gain- or loss-of-function screening using chromosome-segment deletions, and applies it to identify metabolic engineering targets in B. subtilis.
bioRxiv · Jan 31, 2024 · PreprintBioengineering