ImmunologybioRxivPreprint
Themis and Grb2 form a constitutive structural hub in T cell receptor signalling
Danielle M. Clancy, Alba Sanz-Sanjuan, Elisabeth Gilis…·Savvas N. Savvides
This study determines the cryo-EM structure of the Themis-Grb2 complex, revealing its role as a dynamic structural hub in T cell receptor signaling and its functional importance in T cell development.