Author

Imke Velghe

Ghent University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alba Sanz-Sanjuan· 1 shared Álvaro Furones Cuadrado· 1 shared Danielle M. ClancyiD· 1 shared Dirk Elewaut· 1 shared Elisabeth GilisiD· 1 shared Jan FélixiD· 1 shared Janine D. BrunneriD· 1 shared Peter Tougaard· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alba Sanz-Sanjuan

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Author profile →

1 paper

Recent·Most cited

Themis and Grb2 form a constitutive structural hub in T cell receptor signalling

Danielle M. Clancy, Alba Sanz-Sanjuan, Elisabeth Gilis, Peter Tougaard, Imke Velghe, Yana Van Droogenbroeck, Jan Félix, Yehudi Bloch, Álvaro Furones Cuadrado, Romain Merceron, Stephan Schenck, Peter Vandenabeele, Janine D. Brunner, Tom Taghon, Dirk Elewaut, Savvas N. Savvides

This study determines the cryo-EM structure of the Themis-Grb2 complex, revealing its role as a dynamic structural hub in T cell receptor signaling and its functional importance in T cell development.

bioRxiv · Feb 16, 2025 · PreprintImmunology