Yang Tang

Developmental PBDE exposure impairs histamine release from mast cells by altering granule maturation and calcium signaling in adult male and female mice

This study shows developmental PBDE exposure impairs mast cell function in adult mice by disrupting granule maturation and calcium signaling, leading to reduced histamine release.

DNA repair functions are essential for bacterial stress defense but render antibiotic tolerant sub-populations susceptible to ciprofloxacin and gentamicin upon prolonged treatment

This study shows that bacterial tolerant subpopulations remain metabolically active and become susceptible to antibiotics targeting DNA and protein synthesis after prolonged stress.